Cancel
OK

You have successfully logged out.

Hello !
chevron_right My profile
chevron_right To My B. Braun overview
Logout

Wound infection management and control

Antimicrobial dressings for infected wounds

Beyond the clinical and economic burden of chronic wound infections, the human impact is also considerable. Symptoms and complications such as pain, malodor, and purulent exudate can negatively impact daily quality of life, comfort, and overall well-being.1

Medical Professional

This information is meant for medical professionals only. Please confirm that you are a medical professional before accessing this information.

Confirm Yes, I am a health care professional. Cancel No, I am not a health care professional.

To address local infection and its symptoms, international consensus documents recognize silver dressings as an appropriate topical antimicrobial choice when clinical signs of wound infection are present.2

United in Care with Askina® Calgitrol® Paste​​

The ionic silver alginate paste designed to support the management of infected and high-risk wounds​

Experience our silver dressings today 


Request a free sample

 

What do you appreciate in your professional care?

Diagram illustrating silver ions (Ag+) interacting with bacteria within an infected wound. It highlights Ag+ ions penetrating and targeting bacteria, suggesting antimicrobial action for infection control.

Reduction of clinical signs ofinfection within the first week oftreatment.3

Reduction of clinical signs of infection

Askina® Calgitrol® Paste ​reduces clinical signs of infection within the first week of treatment and provides a broad antimicrobial effectiveness.3

Immediate availability of silver ions 

Conventional silver dressings rely on wound exudate to release ionic silver, often causing delayed or inconsistent antimicrobial action.

Askina® Calgitrol® Paste, with intrinsic water content, delivers immediate ionic silver release upon application - ensuring effective antimicrobial activity and reducing the risk of suboptimal silver levels during dressing changes.

 

Data on File Internal report use TR 2714

Image showing a close-up of a leg with an open wound being treated with Askina Calgitrol Paste dressing, being applied by a nurse. The wound appears inflamed with surrounding redness, highlighting a medical care or wound treatment context.

High conformability that simplifies care

Askina® Calgitrol® Paste is an innovative silver alginate dressing in the form of a homogeneous paste that closely conforms to the wound bed.3

 

What do your patients appreciate?

Less pain and odor

Askina® Calgitrol® Paste is well tolerated by patients5 and can contribute to pain control6 and odor reduction.7

Illustration of a person walking, with pain indicators shown near the left foot and heat lines near the right leg. The graphic represents the reduction of pain and discomfort during movement, indicating that symptoms are improving

Improved patient comfort and quality of life with Askina® Calgitrol® Paste.​

mage showing a close-up of a leg with an open wound being treated with Askina Calgitrol Paste dressing, being applied by a nurse. The wound appears inflamed with surrounding redness, highlighting a medical care or wound treatment context.

Did you know?

Evidence shows that using a biofilm remover/cleanser together with an antimicrobial is more effective in managing infection than using an antimicrobial alone.7

Download here

 Mode of Action

How intrinsic water content enables immediate and sustained silver ion release

Illustration showing Askina Calgitrol Paste mode of action. The paste is being applied to a wound, highlighting the release of silver ions (Ag+). The diagram emphasizes the antimicrobial action of silver ions interacting with bacteria at the wound site, with labeled molecules and directional arrows indicating ion movement.

Absorption of exudate

The alginate matrix absorbs wound exudate, that naturally contains sodium ions.

Ionic exchange 

Sodium ions replace silver ions in the alginate matrix breaking internal bonds and releasing silver ions.

Sustained release 

Thanks to this mechanism silver ions are continuously released into the wound bed, providing controlled and an antimicrobial effectiveness.

Askina® Calgitrol® Ag+

A versatile portfolio of silver dressings tailored to meet wound and patient needs

United in Care with Askina® Calgitrol® Ag+

The antimicrobial silver dressing with strengthening cellulose fiber to manage wound infection and high exudate.

Specially intended for flat superficial highly exuding wounds.

 

What do your patients appreciate?

Wound healing in a moist environment​

Askina Calgitrol Ag+​ promotes wound healing in moist wound environment8 by reducing bacterial growth, while maintaining low cytoxicity.9

Illustration of a healing wound, with directional arrows highlighting the wound closure process and the reduction in wound size as healing progresses.

Effective against common pathogens, including gram-positive and gram-negative bacteria such as E. coli and MRSA.​

Reduces pain and wound trauma

Askina Calgitrol Ag+ gelling formation traps, locks in and controls bacteria away from the wound bed, while reducing pain and trauma upon removal.10

Illustration of a patient raising their arms in celebration, symbolizing reduced wound pain and trauma.

The product reduces pain upon removal and trauma to the wound when used in a moderate to highly exuding wound.​

Mode of action of Askina® Calgitrol® Ag+ 

Discover the mode of action of Askina® Calgitrol® Ag+ and why silver dressings are a game changer in managing wound infections. 

All open wounds are contaminated or colonized with microorganisms; however, not all contaminated wounds become infected. The symbiotic relationship between the host and the colonizing microorganism becomes pathogenic when the host’s immune system becomes compromised by the virulence of organisms present within a wound, and wound infection occurs. Biofilms also contribute to delayed wound healing and increase the risk of wound infection.11

Local infection is used to refer to a stage of infection in which there is presence and proliferation of microorganisms within the wound that evoke a response from the host, often including a delay in wound healing. Local infection is contained within the wound and the immediate peri-wound region (less than 2cm). Local infection often presents as covert (subtle) signs and symptoms, that may not be immediately recognized as a sign of infection.

Covert (subtle) signs and symptoms of wound infection include: Hypergranulation, Bleeding, friable granulation, Epithelial bridging and pocketing in granulation tissue, Increasing exudate, Delayed wound healing beyond expectations.

As local wound infection progresses, classic cardinal (overt) signs and symptoms that are traditionally associated with local infections generally become evident:  erythema, local warmth, swelling, purulent discharge, wound breakdown and enlargement, pain and increasing malodour.11

Silver has a long and intriguing history as an antimicrobial in human healthcare. Silver has broad-spectrum antimicrobial activity, including against resistant microorganisms, and inhibits biofilms that are highly resistant to conventional treatments.12In wound dressings silver is used in various forms.13

Clinical guidelines recommend that silver dressings are used for wounds where infection is already established or an excessive wound bioburden is delaying healing ('critical colonization' or 'pre-infection'), and that they are used for short periods before re-evaluation. Silver dressings should not be used in the absence of localized (overt or covert), spreading or systemic infection, unless there are clear indicators that the wound is at high risk of infection or re-infection.14

A recent consensus recommended utilizing a ‘2-week challenge’ to determine the efficacy of an antimicrobial (specifically silver dressings). After 2 weeks it should be determined whether the wound has improved and whether there are any continuing signs of infection.15

Take the first step toward better healing – Discover Askina® Calgitrol® today!​

Please fill out the contact form to request a visit from a sales representative to test Prontosan® products or get more information.

B. Braun in Malaysia is the responsible organization

The protection of the personal data of our customers is very important to us and we take it very seriously. Your personal data is subject to data protection and will only be collected and stored for approach reasons. Under no circumstances will we pass on your personal data to third parties outside of the B. Braun group or use or store them for any other purposes. Our staff has been trained to handle personal data and is obliged to comply with the data protection regulations.

Thank you for your request.

check_circle

Kindly check your inbox and confirm the email we've sent you.

Your request could not be submitted. Please try again.

warning

References

1. Probst S, Apelqvist J, Bjarnsholt T, Lipsky BA, Ousey K, Peters EJG. Antimicrobials and Non-Healing Wounds: An Update. Journal of Wound Management 2022; 23 (S1):1-33. European Wound Management Association (EWMA). https://www.amr-insights.eu/antimicrobials-andnon-healing-wounds-anup ​

2. International Wound Infection Institute (IWII). Wound Infection in Clinical Practice: Principles of Best Practice. Wounds International; 2022.​

3. Chadwick P. International case series: Using Askina® Calgitrol® Paste in the treatment of diabetic foot infection: case studies. London: Wounds International, 2013:1-9.​

4. B. Braun (2011). Log Reduction (LR) measure of efficacy (results only) of Askina® Calgitrol® Paste and Flamazine Cream against a culture of methicillin resistant Staphylococcus aureus (MRSA, ATCC BAA-44). Report HOSP 303, B. Braun Hospicare Ltd. cited in: Chadwick P. Askina® Calgitrol® Paste in the treatment of diabetic foot infection. Wounds International; 2013: 1-9.​

5. Nicodeme M, Cheron M, Kriegel I, Jaimes H, Fromantin I. A silver alginate paste dressing in the management of non-malignant wounds with signs of infection in oncology patients: an observational prospective case series. Wounds International 2021; 12 (3):70-7​

6. Forma O, Basile D. Wound dressings without pain: A new paste formulation of an antiseptic dressing with alginate and silver ions. World Union of Wound Healing Societies congress 2016.​

7. Naude L. The use of Prontosan® in combination with Askina® Calgitrol®: an independent case series. Wounds International 2018; 9 (1): 44-8.7. Naude L. The use of Prontosan® in combination with Askina® Calgitrol®: an independent case series. Wounds International 2018;9(1):44-8.​

8. Report Antimicrobial Stability Results Summary - External Report​

9. Observational Study Protocol​

10. IOV (Traceability) Matrix, Design Verification Protocol, Design Validation Report​

11. International Wound Infection Institute. Wound Infection in Clinical Practice: Principles of Best Practice. Wounds International; 2022. ​

12. Du, Y.; Lu, J.; Guo, X.; Xia, Z.; Ji, S. The Role of Silver and Silver-Based Products in Wound Management: A Review of Advances and Current Landscape. Journal of Functional Biomaterials. 2026;17(1):27. https://doi.org/10.3390/jfb17010027​

13. Rippon MG, Rogers AA. Development of silver resistance: a focus on wound care. Wounds International. 2025;16(2):20–37.​

14. International consensus. Appropriate use of silver dressings in wounds. An expert working group consensus. London: Wounds International, 2012.​​

15. World Union of Wound Healing Societies (WUWHS), Florence Congress, Position Document. Management of Biofilm. Wounds International 2016.

We value your privacy

We use cookies to enable all functionalities for best performance during your visit and to improve our services by giving us some insight into how the website is being used. Continued use of our website without having changed your browser settings confirms your acceptance of these cookies. For details, please see our privacy policy.